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What Is Alzheimer’s Disease?

Alzhimers.GovMay 6, 2025

Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks. People with Alzheimer’s also experience changes in behavior and personality.

A gene guiding brain cell growth may regulate Alzheimer’s plaque size and toxicity

Alzhimers.GovApril 10, 2025

An NIH-funded study suggests that the gene PLXNB1 affects the size and toxicity of beta-amyloid plaques by regulating how glial cells form netlike structures around these proteins. A hallmark of Alzheimer’s disease, beta-amyloid plaques are sticky buildups of protein in the brain. These findings, published in Nature Neuroscience, may offer new directions for developing treatments […]