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Advance Directives and Health Care Planning Resources after Diagnosis

Alzhimers.GovSeptember 2, 2025

Advance directives are legal documents that outline your preferences and apply only if you are unable to speak for yourself. When it comes to health care planning, advance directives can help share your wishes about medical treatment you’d like to receive in the event of an emergency.

Can I Prevent Dementia?

Alzhimers.GovAugust 26, 2025

As you age, you may have concerns about the increased risk of dementia. You may have questions, too. Are there steps I can take to prevent it? Is there anything I can do to reduce my risk? There are currently no approaches that have been proven to prevent Alzheimer’s disease and related dementias. However, as […]

What Is Alzheimer’s Disease?

Alzhimers.GovMay 6, 2025

Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks. People with Alzheimer’s also experience changes in behavior and personality.

A gene guiding brain cell growth may regulate Alzheimer’s plaque size and toxicity

Alzhimers.GovApril 10, 2025

An NIH-funded study suggests that the gene PLXNB1 affects the size and toxicity of beta-amyloid plaques by regulating how glial cells form netlike structures around these proteins. A hallmark of Alzheimer’s disease, beta-amyloid plaques are sticky buildups of protein in the brain. These findings, published in Nature Neuroscience, may offer new directions for developing treatments […]