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Designing Self-Destructing Bacteria to Make Effective Tuberculosis Vaccines
Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with “”kill switches”” that can be triggered to stop the bacteria after they activate an immune response. Two preclinical studies, published, Jan. 10 in Nature Microbiology, tackle the challenge of engineering bacteria that are safe for use […]

Difficulty managing bills may signal early dementia
Financial challenges such as missed credit card and mortgage payments may indicate early stages of dementia long before a formal diagnosis, according to an NIA-funded study.

Toward improved early detection of pancreatic cancer
The discovery of a ‘biomarker panel’ could have a profound impact on the ability to identify patients at risk of developing PC at an earlier stage

Researchers develop AI model to automatically segment MRI images
Research scientists in Switzerland have developed and tested a robust AI model that automatically segments major anatomic structures in MRI images, independent of sequence. In the study, the model outperformed other publicly available tools.

CAR T-cells enable record-breaking 18-year nerve cancer remission
A cancer therapy that uses genetically engineered immune cells, called CAR T-cells, has kept a person free of a potentially fatal nerve tumour for a record-breaking 18 years.

Pancreatic cancer: blocked nerves as a possible new treatment strategy
Pancreatic cancer is fueled by connections to the nervous system. The team discovered that the tumor reprograms the neurons for its own benefit.

A diabetes, heart failure, and kidney disease medication is the first of its kind to significantly reduce both heart attacks and strokes
New research shows sotagliflozin is the only drug in its class to demonstrate these results.

Research in Context: Detecting cancer
Researchers have made huge strides in learning how to detect signs of cancer in bodily fluids like blood, saliva, and urine. Learn how these liquid biopsies are being tested to aid early cancer detection and guide treatment.

Researchers Discover the Brain Cells That Tell You to Stop Eating
Newly discovered brain cells count each bite before sending the order to cease eating a meal.

Sleeping pills stop the brain’s system for cleaning out waste
A specialized system sends pulses of pressure through the fluids in our brain.